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loperamide binding to opioid receptors in the intestinal wall and inhibits acetylcholine release of prostaglandins, thereby reducing the increasing motility and transit time through proviron side effects the intestine contents. It improves the tone of the anal sphincter, thereby reducing incontinence of stool and the urge to defecate,tablets for sucking bioequivalent Imodium capsules and tablets with a film coating.  Subjected to intensive metabolism in the process of oxidative N-demethylation in the “first” passage through the liver.
Write mainly through the gastrointestinal tract  with feces, a small portion excreted in the urine (in the form of conjugated metabolites).

Indications

  • acute and chronic diarrhea
  • regulation of the chair in patients with iliostomaContraindications
  • children’s age (up to 6 years);
  • hypersensitivity to loperamide and / or other components of the drug;
  • acute dysentery and other infections of the gastrointestinal tract (caused, including Salmonella, Shigella and Campylobacter);
  • ileus (including avoided peristalsis suppression if necessary), diverticulosis, acute ulcerative colitis or pseudomembranous enterocolitis (diarrhea caused by taking antibiotics);
  • first trimester of pregnancy
  • lactation.Carefully:
  • with hepatic insufficiencyPregnancy and lactation
    Although there is no indication of teratogenic or embryotoxic effects, Imodium during pregnancy can be proviron side effects given only if the expected benefit of therapy to the mother outweighs the potential risk to the fetus.During the first trimester of pregnancy is contraindicated receive Imodium. Since small amounts of the drug can penetrate into breast milk intake lozenge during breast feeding is contraindicated.

    Dosing and Administration
    Inside. The tablet is placed on the tongue for a few seconds, it dissolves, after which it is swallowed with the saliva without drinking water.
    Adults, including the elderly, and children over 6 years: Acute diarrhea: the initial dose – 2 tablets (4 mg) for adults 1 tablet (2 mg) for children, after taking 1 tablet (2 mg) after each defecation in the case of liquid stool. Chronic diarrhea: the initial dose – 2 tablets (4 mg) per day for adults and one tablet (2 mg) for children; more usually, this dose is individually adjusted so that the stool frequency was 1-2 times per day, which is usually achieved with a maintenance dose of 1 to 6 tablets per day.

    . The maximum daily dose for acute and chronic diarrhea in adults – 8 tablets (16 mg); children maximum daily dose is calculated on the basis of body weight (3 tablets per 20 kg body weight of the child – 8 tablets (16 mg)).
    When a normal chair or stool in the absence of the drug over 12 hours overturned.

    Side effect

  • allergic reactions (skin rash);
  • constipation and / or bloating;
  • intestinal colic;
  • retention of urine (rare);
  • ileus (very rare);
  • pain or discomfort in the abdomen;
  • nausea, vomiting;
  • fatigue;
  • drowsiness, dizziness;
  • dry mouth;
  • burning sensation or tingling tongue, occurs immediately after taking the tablets for sucking.Overdose

    Symptoms:
    depression of the central nervous system (CNS): stupor, incoordination, drowsiness, cramps, increased muscle tone, respiratory depression; ileus. Children are more sensitive to the effects on the CNS.

    Treatment
    Treatment is symptomatic: gastric proviron side effects lavage, activated charcoal (not later than 3 hours after taking Imodium), mechanical ventilation. The antidote – naloxone. Since the duration of action of Imodium more than the naloxone (1-3 hours), you may need to re-appointment of the latter. To detect possible CNS depression the patient should be monitored closely for at least 48 hours.

    Interactions with other drugs not mentioned.

    Cautions
    As lozenges are quite fragile, to avoid damage to them can not push through the foil. In order to get the pill from the blister is necessary to take the foil over the edge, completely remove it from the wells in which the tablet and gently push the bottom, remove the tablet from the packaging.
    The drug should be discontinued immediately if developing constipation or bloating.
    Because the treatment of diarrhea Imodium is only symptomatic, it is necessary, along with, possibly, means to apply etiotropic. Patients with diarrhea, especially among children, and may appear hypovolemia reduction electrolyte content. In such cases, the most important is the replacement therapy to replenish fluids and electrolytes.
    In acute diarrhea, if 48 hours is not observed clinical improvement, taking Imodium should stop and eliminate infectious genesis of diarrhea.
    Do not use for diarrhea accompanied by blood in stool and high temperature.
    In patients with AIDS, treatment should be discontinued immediately at the first signs of bloating. In some cases in AIDS patients with infectious colitis both viral and bacterial origin in the treatment Imodium may develop toxic expansion of the colon.
    Patients with hepatic impairment should be monitored carefully for signs of toxic damage.
    During treatment, it is recommended to diet and fluid replacement .

    The impact of the drug on the ability to drive and control technology
    in the period of treatment should refrain from driving and transport activities potentially hazardous activities that require high concentration and psychomotor speed reactions.

    Form release
    1 or 2 blisters of aluminum / aluminum containing 10 tablets in a carton box with instruction on the medical application.

    Shelf life
    5 years

    Storage:
    At a temperature of 15 to 30 ° C out of proviron side effects reach of children.

    Conditions of supply of pharmacies
    without a prescription.

 

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Hypnotic from the group tsiklopirrolonov. It has the following pharmacological properties: hypnotic, sedative, tranquilizing, anticonvulsant and muscle relaxant. These effects zopiclone associated with a specific agonistic effect omega receptors (known previously called benzodiazepine receptors type I and type II), relating to a macromolecular complex proviron buy modulating opening neuronal ion channels chlorine. Zopiclone has the property to reduce the time to sleep and the frequency of nocturnal and early awakenings, increase the duration of sleep and improve the quality of sleep and awakening. These effects when using the drug in recommended doses, combined with a characteristic electroencephalographic profile, which differs from the one recorded when taking benzodiazepines.

Pharmacokinetics Absorption Zopiclone is rapidly absorbed. Food does not affect the absorption. Peak plasma concentrations are reached within 1.5-2 hours and constitute approximately 30 and 60 ng / ml after oral administration of 3.75 mg and 7.5 mg, respectively. The absorption of the drug does not depend on gender.Distribution Relationship to plasma proteins is low (approximately 45%), and insatiable. The risk of interaction with other drugs in contact with the protein level is very low. The drug is rapidly distributed from the systemic circulation. The volume of distribution 91,8-10,4 liters. Drug concentrations in breast milk are similar to those in plasma. According to calculations, delivery of the drug to the baby through breast milk proviron buy will not exceed 1% of the dose adopted mother for 24 hours.Metabolism After repeated taking the drug accumulation of zopiclone and its metabolites occurs. Interindividual differences are insignificant. Zopiclone is extensively metabolized in the human body to two main metabolites: N-oxide zopiclone and N-demethyl zopiclone. Studies in vitro indicated that the cytochrome P450 (CYP) is the major isoenzyme ZA4, through which the metabolism of zopiclone and the formation of two metabolites. In addition, participating in the metabolism of zopiclone isoenzyme CYP2C8, by means of which also forms a second metabolite (N-demethyl zopiclone). The half-life of the metabolites according excretion in the urine is approximately 4.5 and 7.4 hours respectively Withdrawal At recommended doses, elimination half-life of unchanged zopiclone is approximately 5 hours. Low renal clearance values unchanged zopiclone (8.4 ml / min) compared with the values of its plasma clearance (232 mL / min) indicate that zopiclone clearance is mainly metabolic. Zopiclone excreted proviron buy in the urine mainly as free metabolites (N derivative -oxide and N-demethyl) (approximately 80%) and feces (about 16%). Separate groups of patients

 

Elderly patients
Despite the slight decrease in hepatic metabolism and lengthening of elimination half-life of approximately 7 hours, even when multiple destination is no evidence of drug accumulation in the plasma.

  • Patients with renal impairment
    even after long-term use is not revealed accumulation of zopiclone or its metabolites. Zopiclone penetrates through the dialysis membrane, but the treatment peredozizirovki proviron buy hemodialysis is ineffective due to the large volume of distribution of zopiclone.
  • Patients with liver failure
    patients with liver cirrhosis the clearance of zopiclone is reduced by approximately 40% in accordance with the decrease demethylation.Therefore, these patients require dose correction.Indications
    Treatment of transient, situational or chronic insomnia in adults (including difficulty falling asleep, night and early awakening).

    Contraindications

  • Hypersensitivity to zopiclone or any other components of the preparation.
  • Myasthenia gravis (myasthenia gravis).
  • Severe respiratory insufficiency.
  • Severe liver failure (acute and chronic) (risk of encephalopathy).
  • Severe sleep apnea syndrome.
  • Age up to 18 years.
  • Hypersensitivity or intolerance to gluten, as part of the preparation contains wheat starch.
  • Galactose intolerance, lactase deficiency or glucose-galactose malabsorption.The caution
    in individuals with alcohol, drug or drug addiction in history, while patients taking alcohol or other psychotropic substances or drugs (increased risk of dependence or abuse).

    Pregnancy and lactation
    is not recommended to use the drug during pregnancy and prescribe nursing mothers.
    If zopiclone is used during the third trimester of pregnancy or during labor, in connection with the pharmacological effects of the drug in the newborn can expect the emergence of hypothermia, hypotension, and respiratory depression.
    In the case of appointment drug imovan ® women of childbearing age should be warned that in the event of planning a pregnancy or suspected pregnancy, they should consult their doctor for discontinuation.

    Dosing and Administration Inside. Treatment should be short-lived as possible and not exceed four weeks, including the period of dose reduction. Extension of deadlines for the proviron buy treatment of more than the maximum allowable carried out after re-evaluation of the patient’s condition. Treatment should always start with the lowest effective dose and will never exceed a maximum dose. The drug is taken immediately before going to a night’s sleep. The duration of treatment

  • Transient insomnia: 2 to 5 days (for example, caused by the change of the place while traveling).
  • Situational insomnia: 2 to 3 weeks.
  • Chronic insomnia: long term treatment is prescribed after consultation with a specialist. Recommended doses
  • For adults (under 65 years): The recommended daily dose is 7.5 mg.
  • For elderly patients (over 65 years), patients with impaired hepatic function or with respiratory moderate insufficiency: The recommended daily dose is 3.75 mg. Only in exceptional cases, the daily dose may be increased to 7.5 mg.

For patients with renal failure despite the fact that the renal disease drug accumulation is not detected or its metabolites, patients with renal failure should begin with a dose of 3.75 mg per day.
In all cases, the daily dose of the drug imovan ® should not exceed 7 5 mg

Side effects:
Bitter taste in the mouth (the most common side effect observed in the appointment of zopiclone).
Dizziness, headache, residual sleepiness after waking; muscular hypotonia, asthenia, reduced libido, diplopia. Digestive disorders: . dyspepsia, nausea, dry mouth, allergic skin reactions , such as itching and rashes, are extremely rare Angioedema and / or anaphylactic reactions. anterograde amnesia can also occur anterograde amnesia ( the risk of its occurrence is increased in proportion to dose).Psychiatric and paradoxical reactions rare: nightmares, irritability, confusion, hallucinations, aggression, depressed mood, incoordination, depression, improper behavior that may be associated with amnesia, walking in a dream. Physical and psychic dependence (even when used in therapeutic doses) syndrome of “lifting” – was observed after discontinuation of treatment (see also “Special instructions”.). Its symptoms vary and can manifest itself in the form of rebound insomnia, anxiety, tremors, excessive sweating, excitement, confusion, headache, palpitations, tachycardia, delirium, nightmares, hallucinations and irritability. In very rare cases may develop seizures. Increase of “liver” enzymes were reported isolated cases of slight increase in serum concentrations of transaminases and / or alkaline phosphatase.

 

Overdose Signs and symptoms of overdose is usually manifested in the form of varying degrees of symptoms of central nervous system depression of somnolence to coma, depending upon the amount of drug received. In mild cases, the symptoms are expressed in sleepiness, confusion, apathy. In more serious cases, symptoms may be expressed in ataxia, lethargy, hypotension, respiratory depression and coma. Rarely proviron buy – atrioventricular block. Overdose is not a threat to life unless combined with other means of reception, a depressing effect on the central nervous system (including alcohol). Other risk factors such as concomitant disease and the weakened condition of the patient may increase the symptoms and even (very rarely) result in death. Treatment If necessary, it is recommended symptomatic and supportive therapy in a hospital. Particular attention should be paid to respiratory and serdechnochno-sudistoy functions. Gastric lavage or activated carbon is only effective if carried out shortly after ingestion. Hemodialysis has small importance because of the large volume of distribution of zopiclone Flumazenil may be used as an antidote.

Drug Interactions With alcohol Alcohol may enhance the sedative effect of zopiclone. Not recommended simultaneous reception of zopiclone and alcohol. With the drugs depressing the central nervous system: neuroleptics, barbiturates, hypnotics, tranquilizers, sedatives, antidepressants with sedative effect (amitriptyline, doxepin, mianserin, mirtazapine, trimipramine), narcotic analgesics, and antitussives ( except buprenorphine, interaction with buprenorphine, see below), antiepileptic drugs, anesthetics, antihistamines with sedative effect, antihypertensive drugs central action, baclofen, thalidomide, pizotifenom a joint application of these drugs with zopiclone may be increased inhibitory action on the central nervous system, including respiratory depression (particularly when using derivatives of morphine, and barbiturates). with trimipramine addition to the above zopiclone reduces the concentration trimipramine plasma and its effect. On the buprenorphine increased risk of respiratory depression including death. Since inhibitors of CYP ZA4, such as erythromycin, clarithromycin, ketoconazole, itraconazole and ritonavir. since zopiclone is metabolised via CYP3A4, CYP3A4 inhibitors that may increase the plasma concentration of zopiclone. At the same time their destination may require dose reduction of zopiclone. Effect of erythromycin on the pharmacokinetics of zopiclone has been studied in 10 healthy volunteers. The area proviron buy under the concentration-time curve (concentration-time) zopiclone was increased by 80% in the presence of erythromycin. With inducers of CYP3A4: such as rifampicin, carbamazepine, phenobarbital, phenytoin, St John’s wort. Since zopiclone is metabolised via CYP3A4, the CYP3A4 inducers may reduce the plasma concentration zopiclone. At their simultaneous appointment may require increased doses of zopiclone.

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Immunorm is of vegetable origin
Its constituent substances polysaccharide have immunomodulatory and anti-inflammatory effects. It stimulates mainly cell-mediated immunity, increasing the number of white blood cells proviron libido and increasing the phagocytic activity of granulocytes.Prevention and treatment of repetitive (recurrent) infections of the respiratory and urinary tracts.In case of recurrent infections of the respiratory tract diseases associated with prolonged retention of complaints, dyspnoea, fever or purulent or bloody sputum, should consult a physician. When in the field of urinary tract complaints reoccurs necessary medical examination and regular medical control in the future. No matter whether released in the urine blood or not, in the presence of heat and retaining complaints not later than 5 days, you need to re-apply to the doctor.

Dosage and administration:

If not indicated differently, the adults and children over 12 years take 1 tablet IMMUNORM- tablets of 100 mg 3-4 times a day.
Tablets can suck, chew or proviron libido drink water. Hours tablets is independent of meal times. Duration of treatment or prophylactic application should not exceed 8 weeks.

Side effects:
In some cases, there may be hypersensitivity reactions to the drug.
When intolerance of drugs from plant material observed a rash, itching, rarely – swelling of the face, shortness of breath, sweating.
Should be discontinued immediately in these cases, treatment and seek medical advice.

 

Contraindications:

The drug IMMUNORM – 100 mg tablets is contraindicated in:
– hypersensitivity to the active substance or other substances forming part of the formulation;
– progressive systemic diseases: tuberculosis, leukemia and leukemia, rheumatic diseases of the connective tissue (collagen), multiple sclerosis;
– AIDS and HIV infection;
-. other autoimmune diseases
while taking IMMUNORM drug proviron libido – 100 mg tablets at the same time you can not use other immunomodulators.

Warning:
Patients with congenital fructose intolerance can begin treatment only after consulting your doctor.

Use during pregnancy and lactation:
In the absence so far of adequate studies IMMUNORM drug – 100 mg tablets are not recommended for use during pregnancy and lactation.

 

Interaction with other drugs:

Reaction with other drugs hitherto proviron libido not been described.

 

Overdose:

Cases of overdose and toxicity has not yet been described. Special intoxication therapy is not known.

Habituation effects:
Not found.

 

Product form:

10 tablets in blisters; 2 or 5 contour cell packages, along with information for the consumer in the box.

 

Storage conditions:

Store under normal conditions.
Keep out of the reach of children.

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Immunomax strengthens the immune defense against viral and bacterial infections. Immunopharmacological mechanisms of drug action consists in the fact that Immunomax activates the following parts of the immune system.Immunomax enhances protection against bayer proviron infections caused by viruses (human papilloma virus, herpes simplex virus, parvovirus, canine distemper virus, etc.) Or bacteria (E. coli, Salmonella, Staphylococcus aureus, chlamydia, mycoplasma, ureaplasma, etc.). This action of the drug is in adults and infants when administered Immunomax different routes: intramuscularly, intravenously, intraperitoneally, per os.Bayer proviron the drug has not been studied in connection with its peptidoglycan nature and very small doses applicable.

Indications

  • for correcting impaired immunity;
  • for the treatment of pathological states (condylomata, warts, dysplasia, and others.) caused by human papillomavirus;
  • for the treatment of infections caused by the herpes simplex virus, chlamydia, mycoplasma, ureaplasma, and other bacteria and viruses.

Pregnancy and lactation
Immunomax should not be used during pregnancy unless the benefits accruing to the patient, do not exceed the potential risk to the fetus. Immunomax not recommended for breastfeeding mothers.

Dosage and administration
Before the use of the drug is dissolved in 1 ml of water for injection. The recommended dose for adults and children 12 years and older is 100-200 IU, depending on the severity of the disease. The drug is administered intramuscularly, once a day. Treatments – 6 injections of 1.2, 3.8, 9 and 10 days of treatment.

For the treatment of recurrent anogenital warts, a course of 6 injections of 200 U Immunomax combined with the destruction of warts by one of the conventional techniques: cryosurgery, electrocoagulation, laser destruction or solkoderm.

For the treatment of infections caused by bacteria or viruses, a course of 6 injections of 100-200 U Immunomax;

To correct a weakened immune system a bayer proviron course of 3-6 injections of 100-200 U Immunomax.

Side effects
not found.

Interaction with other medicinal products
are not described.

Release form
Valium for drug of a solution for intramuscular injection of 100 IU or 200 IU in vial or ampule.

– 3 vials or ampoules of the drug together with instructions for use in a cardboard box;

– 1 bottle or vial of medication, 1 vial of water for injection 2 ml injection syringe 1 sterile disposable 2 mL, 1 napkin predinektsionnuyu together with instructions for use in a cardboard box;

– 3 vial or ampoule with a drug, 3 vials with water for injection 2 ml, 3 Sterile disposable injection syringe bayer proviron 2 ml, 3 predinektsionnye napkin together with instructions for use in a cardboard box;

– 30 vials or ampoules with medication with instructions for use 5 -in a cardboard box (for hospitals).

Storage conditions
of the reach of children at a temperature from +4 to + 8 ° C.

Shelf life
2 years. Do not use beyond bayer proviron the expiration date.

Conditions of supply of pharmacies
on medical prescription. steroiden kaufen

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Immunomax strengthens the immune defense against viral and bacterial infections. Immunopharmacological mechanisms of drug action consists in the fact that Immunomax proviron activates the following parts of the immune system , Immunomax enhances protection against infections caused by viruses (human papilloma virus, herpes simplex virus, parvovirus, canine distemper virus, etc.) Or bacteria (E. coli, Salmonella, Staphylococcus aureus, chlamydia, mycoplasma, ureaplasma, etc.). This action of the drug is in adults and infants when administered Immunomax different ways:. Intramuscularly, intravenously, intraperitoneally, per os proviron the drug has not been proviron studied in connection with its peptidoglycan nature and very small doses applicable.

Indications

  • for correcting impaired immunity;
  • for the treatment of pathological states (condylomata, warts, dysplasia, and others.) caused by human papillomavirus;
  • for the treatment of infections caused by the herpes simplex virus, chlamydia, mycoplasma, ureaplasma, and other bacteria and viruses.

Pregnancy and lactation
Immunomax should not be used during pregnancy unless the benefits accruing to the patient, do not exceed the potential risk to the fetus. Immunomax not recommended for breastfeeding mothers.

Dosage and administration
Before the use of the drug is dissolved in 1 ml of water for injection.
The recommended dose for adults and children 12 years and older is 100-200 IU, depending on the severity of the disease. The drug is administered intramuscularly, once a day. . The course of treatment – 6 injections of 1.2, 3.8, 9, 10 days of treatment
for the treatment of recurrent anogenital warts course from the 6 injections of 200 U Immunomax combined with the destruction of warts by one of the conventional techniques: cryosurgery, electrocoagulation, laser destruction or solkoderm .
For the treatment of infections caused by bacteria or viruses, a course of 6 injections of 100-200 U proviron Immunomax;
To correct a weakened immune system a course of 3-6 injections of 100-200 U Immunomax.

Side effects
not found.

Interaction with other medicinal products
are not described.

Release form
Valium for drug of a solution for intramuscular injection of 100 IU or 200 IU in vial or ampule.

– 3 vials or ampoules of the drug together with instructions for use in a cardboard box;

– 1 bottle or vial of medication, 1 vial of water for injection 2 ml injection syringe 1 sterile disposable 2 mL, 1 napkin predinektsionnuyu together with instructions for use in a cardboard box;

– 3 vial or ampoule with proviron a drug, 3 vials with water for injection 2 ml, 3 Sterile disposable injection syringe 2 ml, 3 predinektsionnye napkin together with instructions for use in a cardboard box;

– 30 vials or ampoules with medication with instructions for use 5 -in a cardboard box (for hospitals).

Storage conditions
of the reach of children at a temperature from +4 to + 8 ° C.

Shelf life
2 years. Do not use beyond the expiration date.

Conditions of supply of pharmacies
on medical prescription. buy melanotan 1 online